Understanding and Managing Stomatitis: A Comprehensive Guide to Mouth Sores

June 30, 2025 | 4 min read
Stomatitis refers to inflammation and soreness that can occur anywhere inside the mouth, including the cheeks, gums, tongue, lips, and palate. This common condition can make eating, talking, and sleeping difficult, impacting overall quality of life. There are several types of stomatitis, with canker sores and cold sores being among the most common. Canker sores, or aphthous ulcers, appear as single pale or yellow ulcers with a red ring, often found on the cheeks, tongue, or inner lip. They can be painful, typically last 5 to 10 days, and tend to recur, but are not contagious or associated with fever. In contrast, cold sores, also known as fever blisters, are fluid-filled sores that usually form on or around the lips. They rarely appear on the gums or roof of the mouth and are often preceded by tingling, tenderness, or burning sensations. Cold sores are caused by the herpes simplex type 1 virus and are highly contagious from the time they rupture until they are fully healed. Unlike canker sores, they can be accompanied by cold or flu-like symptoms and tend to recur in the same location when reactivated by factors like stress, fever, or hormonal changes. Beyond canker and cold sores, mouth irritation can stem from various sources. These include physical trauma like biting your cheek, the presence of dental appliances, sharp or broken teeth, and even habits like chewing tobacco. Burns from hot food or drinks, gum disease (gingivitis), and other mouth infections can also lead to stomatitis. Furthermore, certain autoimmune diseases such as lupus, Crohn's disease, or Behcet's disease, as well as specific medications (chemotherapy, antibiotics, rheumatoid arthritis drugs, epilepsy medications) and radiation therapy for cancer, can trigger mouth inflammation. Hypersensitivity to certain foods or medicines can also contribute. The exact cause of canker sores remains unknown, but several factors are believed to contribute, including certain medications, mouth trauma, nutritional deficiencies (like vitamin B12 or folate), stress, bacterial or viral infections, lack of sleep, sudden weight loss, and specific foods like potatoes, citrus fruits, and chocolate. Canker sores may also be linked to a temporarily weakened immune system, hormonal shifts, or genetic predisposition; they are considered an autoimmune condition and are not contagious. For both types of sores, treatment generally aims to alleviate symptoms. Most mouth sores heal within two weeks, even without intervention. Identifying and addressing the underlying cause is ideal, but if not possible, symptom relief becomes the primary focus. Strategies to ease pain and inflammation include avoiding hot, salty, spicy, and citrusy foods and beverages, using pain relievers like acetaminophen or ibuprofen, and gargling with cool water or sucking on ice pops for burns. For canker sores, increasing water intake, rinsing with salt water, and practicing good dental hygiene are beneficial. Topical anesthetics such as lidocaine or xylocaine (not for children under 6) or topical corticosteroids like triamcinolone dental paste can provide relief. Over-the-counter remedies like Blistex and Campho-Phenique may also help, especially if applied early. More severe cases might warrant Lidex gel, Aphthasol paste, or Peridex mouthwash. If canker sores are frequent, testing for folate or vitamin B12 deficiencies may be recommended. Corticosteroids, such as prednisone, are highly effective in reducing swelling and pain for both canker and cold sores (after the viral stage of cold sores). However, it's crucial to discuss any existing health conditions with your doctor before starting new medications, as some, like prednisone, can impact conditions such as diabetes. There is no cure for cold sores, but treatments can manage outbreaks. These include taking antiviral medications like valacyclovir (Valtrex) at the first sign, applying protective antiviral ointments (e.g., 5% acyclovir ointment), or using ice on the lesion. L-lysine tablets and prescribed antiviral medications may also help shorten the duration of blisters. It is important to note that not all mouth sores are harmless. If a mouth sore has not healed within two weeks, it is crucial to schedule an appointment with your doctor for evaluation.

Pro Tip

The content of the article is shared by netizens, please carefully identify it